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ViriCan - Viral Carcinogenesis & Cancer Biology Research Group
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Description: Our research group aims to produce and disseminate knowledge on the role of selected human viruses in the development of human cancers, as well as to contribute for better understanding of the biology of malignant tumors. We conduct studies for a better understanding of the role of carcinogenic viruses, notably the Epstein-Barr virus (EBV) and the Kaposi Sarcoma virus (KSHV), in the etiopathogenesis of cancers in humans, whether in immunocompetent individuals or people living with the human immunodeficiency virus (HIV). Furthermore, we evaluate the possible effects of constitutional factors, viral products, natural products or other compounds on the biological aggressiveness of cancers, particularly by modifying tumor progression phenomena, such as neoplastic invasion and metastatic dissemination. Our studies are mostly based on human lymphomas, carcinomas, and sarcomas as experimental models. We are part of the Sao Paulo State University (UNESP), Botucatu School of Medicine, and our laboratory is located at the Institute for Biotechnology (IBTEC), UNESP, in Botucatu, SP, Brazil. Website: http://virican.net